半導體感測器於精準疾病篩檢之應用

本文探討半導體感測技術在精準疾病篩檢的重要發展，聚焦於生物場效電晶體與微流體晶片的整合應用。文中介紹三種主要生物場效電晶體技術：離子敏感型場效電晶體、石墨烯場效電晶體及矽奈米線場效電晶體，分析其檢測原理與產業應用實例。同時探討微流體晶片透過流體控制與結構設計實現自動化檢體前處理的關鍵作用。生物場效電晶體與微流體技術整合後，可滿足定點照護檢驗對快速、靈敏、操作簡便的核心需求，為精準醫療提供創新解決方案，在傳染病快速檢測、早期疾病篩檢及個人化醫療方面展現巨大潛力。

This article explores the important development of semiconductor sensing technology in precision disease screening, focusing on the integration of biofield-effect transistors and microfluidic chips. The article introduces three major biofield-effect transistor technologies: ion-sensitive field-effect transistors, graphene field-effect transistors, and silicon nanowire field-effect transistors, and analyzes their detection principles and industrial applications. Meanwhile, the key role of the microfluidic wafer in realizing automated inspection pre-processing through fluidic control and structural design will be discussed. The integration of biofield-effect transistors and microfluidic technology can satisfy the core needs of rapid, sensitive, and easy-to-operate point-of-care testing, providing an innovative solution for precision medicine and demonstrating great potential in the rapid detection of infectious diseases, early disease screening, and personalized medicine.